Home Clinical Topics Medications

Medications

First targeted therapy for rare mutation of gastrointestinal stromal tumors

The U.S. Food and Drug Administration (FDA) recently announced the approval of Blueprint Medicines Corporation’s avapritinib (Ayvakit) for the treatment of adult patients with metastatic gastrointestinal stromal tumor (GIST) with the “platelet-derived growth factor...

First FDA-approved treatment for preventing Ebola virus

In late December 2019, the U.S. Food and Drug Administration (FDA) announced the approval of Merck’s Ervebo, the first FDA-approved vaccine to prevent Ebola virus disease. The FDA Deputy Commissioner for Policy, Legislation, and International...

New guidelines for the management of school-based asthma

The Community Preventative Services Task Force (CPSTF) recently released new recommendations around the management of school-based asthma. These management strategies aim to reduce the amount of hospitalizations and emergency room visits from children and...

Potential consideration for physicians regarding cannabis edibles

In early January 2020, the Canadian Medical Association Journal published a commentary from Drs. Jasleen Grewal and Lawrence Loh regarding potential concerns around the use of cannabis edibles. One of the key points addressed in...

FDA issues warning letter for medication-assisted treatment for opioid use disorder

The U.S. Food and Drug Administration (FDA) recently issued a warning letter to Alkermes, Inc. due to misbranding on the drug Vivitrol, which is used to prevent opioid dependence relapse. The letter was issued...

Promoting safe use of parenteral anticoagulants

Nurses can take the lead in preventing harm related to heparin administration. Takeaways Parenteral anticoagulants require appropriate patient teaching to enhance adherence to medication administration. Use of unfractionated heparin/low-molecular weight heparins prevent adverse effects from...

10 years of inpatient diabetes certification— Lessons learned

Commitment and persistence pay off in improved outcomes. Takeaways Lessons learned and best practices from 10 years of Joint Commission inpatient diabetes certification. Changing inpatient culture and behaviors in diabetes care takes repeated data collection...

Potential new targeted therapy for Duchenne muscular dystrophy

The U.S. Food and Drug Administration (FDA) recently granted accelerated approval for Sarepta Therapeutics’ golodirsen (Vyondys 53), an injection for patients with Duchenne muscular dystrophy (DMD) with a mutation in the dystrophin gene “that...
mentoring skills nurse practitioner preceptors post

Nurse and antimicrobial stewardship: Efforts are underway to address the looming crisis

Everyone knows the bad news: Bacterial resistance to antibiotics is common. The good news is that healthcare providers, public health organizations like the Centers for Disease Control and Prevention (CDC) and the World Health...

How Denton County is addressing the diabetes epidemic

The impact of diabetes is well known. In a little over a decade, it’s estimated 54 million people in the United States will be affected, up to 385,800 Americans will die each year and...

Educational interventions to increase Tdap vaccination rates among pregnant women

The highly contagious respiratory infection pertussis remains a public health problem for the United States.1 Infants have the highest morbidity and mortality rates from pertussis because of a lack of immunity at birth and...

Accelerated approval for new sickle cell disease treatment

The U.S. Food and Drug Administration (FDA) recently granted accelerated approval to Global Blood Therapeutics’ voxelotor (Oxbryta), a treatment for adults and pediatric patients (12 years and older) with sickle cell disease (SCD). SCD is...

Legalization of marijuana and schizophrenia

The legalization of marijuana for medicinal and recreational purposes is a hot topic in many states. As a mother and healthcare professional, I feel it is imperative that society be educated about the danger...