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To innovate is to put new ideas into practice or existing ideas into practice in new ways. Innovation isn’t new, but its prominence and need in health care continues to increase. Addressing the complexities of healthcare delivery requires creative solutions and approaches that challenge the status quo. Building a culture of innovation necessitates developing skills that allow for ongoing innovation. For this reason, the American Nurses Association (ANA) is focused on nurse-led innovation for healthcare improvement as a part of its strategic goals.