In older adults with arthritis, opioid use increases the risk of fractures and safety events requiring hospitalization, compared to nonselective NSAIDs (nsNSAIDs) and selective cyclooxygenase 2 inhibitors (coxibs), according to a study in the Archives of Internal Medicine. Opioids, but not coxibs, also increased the risk mortality compared with nsNSAIDs. Read more at here.
