Dosing strategy may reduce toxicity of TB treatment

Giving patients with tuberculosis (TB) lower doses of the bedaquiline together with verapamil might lead to the same antibacterial effects as higher toxic doses of bedaquiline, according to a study of mice published in Antimicrobial Agents and Chemotherapy. The combination could potentially shorten treatment time, reduce the side effects of bedaquiline, and improve patient outcomes. Read more and read the study abstract.


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