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Study fails to show benefit of adding vitamin C to treatment of septic shock

By: Lydia L. Kim, Digital Content Editor

A study recently published in the Journal of the American Medial Association aimed to examine if a treatment combination of vitamin C, hydrocortisone, and thiamine would lead to a “rapid resolution of septic shock” compared to using only hydrocortisone.

The researchers conducted a randomized clinical trial amongst 216 participants, and compared the outcomes between those who received a combination of intravenous vitamin C, hydrocortisone, and thiamine compared to those who received only hydrocortisone.

The data, ultimately, did not revel a connection between the treatment combinations, thus no conclusions were able to be made on the original research question.

Please read more about the study, here.


The views and opinions expressed here are those of the author and do not necessarily reflect the opinions or recommendations of the American Nurses Association, the Editorial Advisory Board members, or the Publisher, Editors and staff of American Nurse Journal. This has not been peer reviewed.

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