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During the peaks and valleys of the now 15-month COVID-19 pandemic, nurses remain the bedrock of competent care, enlightened public health activities, and credible education efforts. In this unprecedented time, nurses in all care settings—from academic medical centers and mass vaccination sites to critical access hospitals and long-term care facilities—have faced many common challenges. To the more than 110,000 who chronicled their experiences in the Pulse on the Nation’s Nurses COVID-19 Survey Series (nursingworld.org/covid-19-survey-series-results) conducted by the American Nurses Foundation (the Foundation), I offer my heartfelt thanks. Your responses have been crucial in helping the American Nurses Association (ANA) and the Foundation understand these impacts and plan and advocate effectively on behalf of the nation’s 4.2 million RNs.