DepressionMental HealthPharmacologyStrictly Clinical

Treatment-resistant depression and the T-rex combination

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By: Gryan Garcia, PhD, PsyD, FNP-BC, PMHNP-BC; Christy Cotner, DNP, FNP-C, PMHNP-BC; and Robert Spano, DNP, FNP-C, PMHNP-BC

The T-Rex combination of Trintellix (vortioxetine) and Rexulti (brexpiprazole) targets multiple neurotransmitter systems, providing a novel and effective approach for managing treatment-resistant depression.

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