Which statement about 2,3 DPG is accurate?

a. It decreases in the presence of epinephrine.

b. It increases as a person ages.

c. It forms when red blood cells synthesize glucose to make adenosine triphosphate.

d. It forms when red blood cells break down glucose to make adenosine triphosphate.

Correct answer: d. A phosphate found in the blood, 2,3-DPG forms when red blood cells break down glucose to make adenosine triphosphate. It decreases hemoglobin’s affinity for oxygen, promoting oxygen release in the tissues.

To learn more, read the continuing nursing education article “Decoding the oxyhemoglobin dissociation curve.”