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Scientists can silence inflammatory gene responsible for a form of breast cancer

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By: Riley Kleemeier

Scientists have found that they are able to “switch off,” or silence, a gene that is responsible for an aggressive form of breast cancer.

Researchers worked with two known breast cancer genes, Rab27a and TRAF31P2, to test the effects of “switching them off.” When the researchers “switched off” the TRAF31P2 gene, they found that this suppressed the growth of the patients’ tumors and prevented metastasis for up to one year. Furthermore, previously existing tumors shrank until undetectable.

The final takeaway from the study concluded that the TRAF3IP2 gene could be targeted in a novel therapeutic approach.

To read more about this study, please click here.

Source: https://www.nature.com/articles/s41598-020-64781-z.epdf?sharing_token=g5pMd4_e6Nk6moKYt8K719RgN0jAjWel9jnR3ZoTv0NqsC8K8p3YcQkhq3pkVMte2MxGIYJilndbyCeof7SHjPMZP5hYcb2EeflxdT2dIdfwhRxJzVCGaDZq4LiDTtpIlqpA9_XIwKptc-BPRuaFkiV58_Sfnm0joShFtH4mRsQ%3D

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